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The third is
Niacatol. This non-flusing
Niacin supplements is one of the best treatments for raising HDL
(good) Cholesterol. For more information click
here.
Its main component is a mixture of higher primary aliphatic alcohols
known as octacosanol. The mixture has been shown to lower cholesterol
in animal models, healthy volunteers, and patients with type II
hypercholesterolemia. For more information click
here.
Policosanol:
A Natural Cholesterol-Balancing Agent
60 caps
per bottle
(1 cap 2 x day)
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Policosanol
is a nutritional supplement extracted from
sugar cane wax. Its main component is a mixture of higher primary
aliphatic alcohols known as octacosanol. The mixture has been
shown to lower cholesterol in animal models, healthy volunteers,
and patients with type II hypercholesterolemia.
Cholesterol-Lowering
Effects
At dosages of 10 mg per day for 4 weeks, policosanol has been shown
to be equally effective as Zocor®
or Pravachol®
at lowering low-density lipoprotein (LDL) and total cholesterol
levels.1 Additionally,
in a study with 85 patients, policosanol was shown to produce significant
cholesterol-lowering effects without causing any serious
adverse reactions in various short- and long-term
studies.2
The profound cholesterol-lowering benefits of policosanol may be
apparent in as little as 6 to 8 weeks—with modest, beneficial
effects resulting after this time period.3
According to
a recent scientific review, 20mg of policosanol per day for 8 weeks
yields the following average results:3
- Lower total
cholesterol levels by 21%
- Lower LDL
levels, or “bad” cholesterol, by 29%
- Increase
high-density lipoprotein (HDL) levels, or “good” cholesterol,
by 15%
Secondary
Cardiovascular Benefits
Not only has policosanol been demonstrated as an effective lipid-lowering
supplement, but it has also been shown to improve other predictive
markers of cardiovascular risk. By supporting the function and integrity
of the endothelium
(blood vessel lining), policosanol may assist in the prevention
of atherosclerosis. In addition, policosanol has also been shown
to reduce blood pressure levels, which may be of particular importance
in older populations wherein concomitant hypercholesterolemia and
hypertension are more frequent.
Specifically, policosanol has been shown to provide the following
additional cardiovascular benefits:
- Prevent
Lipid Peroxidation of LDL. Oxidized LDL cholesterol can contribute
to hardening of the arteries. Policosanol was shown to prevent
LDL oxidation in vitro, suggesting it may support blood vessel
elasticity and flexibility.3
- Inhibit
Smooth Muscle Cell Proliferation. Accelerated smooth muscle cell
proliferation is thought to be a primary factor in the development
of atherosclerotic plaque. In experimental models, policosanol
was shown to significantly reduce smooth muscle cell proliferation,
suggesting it may have a protective effect on the arterial wall.4,5
- Inhibit
Platelet Aggregation. Excessive platelet aggregation can lead
to the formation of blood clots and increased cardiovascular risk.
Research on humans suggests that policosanol inhibits platelet
aggregation, possibly by reducing the formation of thromboxane
A2—a potent inducer of platelet aggregation—and increasing
the production of prostacyclin, which is a potent inhibitor of
platelet aggregation.6
- May
Help to Lower Blood Pressure. Elevated blood pressure and cholesterol
levels often coexist. Human research suggests that policosanol
may help to lower systolic blood pressure levels, which may be
of particular importance in the elderly.7
Conclusion
A high percentage of the U.S. adult population has high cholesterol
levels, which can frequently coexist with other markers of cardiovascular
risk—such as high blood pressure. Sugarcane-derived policosanol
has been shown to significantly improve cholesterol levels, while
simultaneously providing secondary support for other important aspects
of cardiovascular health. Policosanol also has an excellent safety
profile and is easy to use—with effective dosing in as little
as 5 to 20 mg per day. Taken together, these factors make policosanol
an ideal choice for adults who don't want to take a lot of pills,
and desire natural support for healthy cholesterol levels and cardiovascular
health.
References:
1.
Fernández JC, Más R, Castaño G, et al. Comparison
of the efficacy, safety and tolerability of policosanol versus
fluvastatin in elderly hypercholesterolaemic women. Clin Drug
Invest 2001;21(2):103-13.
2. Canetti M, Moreira M, Más R, et al. Effects of policosanol
on primary hypercholesterolemia: a 3-year open-extension follow-up.
Curr Ther Res 1997;58:868-75.
3. Gouni-Berthold I, Berthold H. Policosanol: clinical pharmacology
and therapeutic significance of a new lipid-lowering agent. Am
Heart J 2002;143:356-65.
4. Menéndez R, Más R, Amor A, et al. Effects of
policosanol treatment on the susceptibility of low density lipoprotein
(LDL) isolated from healthy volunteers to oxidative modification
in vitro. Br J Clin Pharmacol 2000;50:255-62.
5. Noa M, Más R, Mesa R. Effect of policosanol on intimal
thickening in rabbit cuffed carotid artery. Int J Cardiol 1998;67(2):125-32.
6. Arruzazabala ML, Noa M, Menéndez R, et al. Protective
effect of policosanol on atherosclerotic lesions in rabbits with
exogenous hypercholesterolemia. Braz J Med Bio Res 2000;33:835-40.
7. Arruzazabala ML, Más R, Molina V, et al. Effect of policosanol
on platelet aggregation in type II hypercholesterolemic patients.
Tissue Reactions 1998;XX(4):119-24.
8. Castaño G, Más R, Fernández JC, et al.
Effects of policosanol on older patients with hypertension and
type II hypercholesterolaemia. Drugs R D 2002;3(3):159-72.
Niacitol:
The best
treatment to raise your good HDL Cholesterol
“Niacin
is the most effective medication in current clinical use for increasing
high-density lipoprotein (HDL) cholesterol. It has the broadest
effect on the lipid profile, reducing all atherogenic apolipoprotein
(apo) B (LDL) and increasing all antiatherogenic apo AI-containing
lipoproteins (HDL), resulting in significant reduction in atherosclerotic
complications and total mortality in trials.” *
The best
treatment to raise your good HDL Cholesterol Niacin is now used
by conventional doctors because it so effectively raises the good
HDL Cholesterol. However, the form of Niacin that most doctors tend
to use causes a hot flushing dilation of the blood vessels in the
face that is very annoying and sometimes painful. This form of Niacin
can also cause damage to the liver at the high doses that is needed
to raise the good HDL Cholesterol.
Niacitol™ is a safer form of Vitamin B3 (Niacin),
known as Inositol Hexaniacinate. It does not cause any adverse flushing
or damage to the liver even at high doses. Niacitol contains 725
mg of Niacin bound to 180 mg of another essential B-vitamin, Inositol.
This combination enhances the benefits and eliminates the side-effects.
The dose I typically recommend is 2 Capsules twice daily with meals.
Clinical trials show that Niacin can raise the good HDL Cholesterol
by more than 25%, lower Total Cholesterol by 7% and your Triglyceride
levels by 29% in 3 months.
To see a chart of natural supplements to treat Cholesterol, including
Niacin, please
click here.
*(Source: Curr
Cardiol Rep. 2003 Nov;5(6):470-6. Niacin, lipids, and heart disease.
Malik S, Kashyap ML. Atherosclerosis Research Center, Department
of Veterans Affairs Healthcare System, Division of Cardiology, University
of California at Irvine, 5901 East Seventh Street (11-111-I), Long
Beach, CA 90822, USA.)
Doctors
Notes:
Over the last
15 years of my medical practice I have witnessed the fact that natural
alternatives to drugs and surgery are not only safer, but also more
effective. My patients are glad to that there are natural alternatives
to the harmful drugs that are being so heavily promoted by doctors
and advertising campaigns today. At the Arizona Institute of Natural
Medicine, our objective is to produce safe and effective natural
alternatives that work without side effects.
Dr.
Clark Hansen, Director of The Arizona Institute of Natural Medicine.

Zocor®
is a registered trademark of Merck & Co., Inc.
Pravachol®
is a registered trademark of Bristol-Myers Squibb Company
Yourvitalhealth.com and our parent company Vital Formulations, Inc.,
has no relationship with either Merck & Co., Inc or Bristol-Myers
Squibb Company, and make no representation that we do.
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