Statin
Drugs:
The
drugs Baycol®, Lescol®,
Lipitor®, Mevacor®, Pravachol®,
and Zocor® are all synthetic HMG CoA Reductase
Inhibitors. These drugs work by inhibiting the production of the
liver enzyme HMG CoA Reductase, which is responsable for the production
of Cholesterol. These drugs are highly concentrated so that they
can be put into very small pills. However, this synthetic manufacturing
process that isolates and concentrates single chemicals can also
cause harmful side-effects. All of these drugs are associated with
causing chemical damage to the liver and muscles. Additionally,
they are known to inhibit the manufacture of CoEnzyme Q10, the heart’s
natural energy molecule. Many physicians believe that these drugs
may cause Congestive Heart Failure if taken over a period several
years.
Bile
Sequestering Drugs:
The bile sequestering Cholesterol lowering drugs Colestid®
and Questran® create deficiencies of fat-soluble
Vitamins A, D, E and K. If taken for several years, these drugs
are also thought to cause Osteoporosis and Cancer.
Cholesterol Trapping Drugs:
Drugs such as Atromid® (Clofibrate) can cause
Gallstones. The World Health Organization found that individuals
who take these drugs have a 36% higher death rate due to cancer
of the Gallbladder than individuals who do not take them.
| Drug |
Action |
Study
Length |
Total
Change |
LDL
Change |
HDL
Change |
TRIG
Change |
Side
Effects |
| Zocor |
HMG
CoA Reductase Inhibitors |
24
Weeks |
-28% |
-38% |
+8% |
-11% |
Inhibits
CoQ10, Muscle Pain, Liver Damage, Kidney Failure, Abdominal
Pain, Gas, Diarrhea
|
| Lipitor |
HMG
CoA Reductase Inhibitors |
12
weeks |
-27% |
-36% |
+7% |
-17% |
Inhibits
CoQ10, Muscle Pain, Liver Damage, Kidney Failure, Abdominal
Pain, Gas, Diarrhea
|
| Pravachol |
HMG
CoA Reductase Inhibitors |
8
weeks |
-24% |
-32% |
+2% |
-11% |
Inhibits
CoQ10, Muscle Pain, Liver Damage, Kidney Failure, Abdominal
Pain, Gas, Diarrhea
|
| Mevacor |
HMG
CoA Reductase Inhibitors |
48
Weeks |
-17% |
-24% |
+6.6% |
-10% |
Inhibits
CoQ10, Muscle Pain, Liver Damage, Kidney Failure, Abdominal
Pain, Gas, Diarrhea
|
| Colestid |
Binds
to Bile, Blocking the Absorption of Cholesterol |
7
months |
-10% |
-10% |
NC |
NC |
Causes
deficiencies of Fat Soluble Vitamins A, D, E, and K; may cause
Osteoporosis and Cancer |
| Atromid |
Traps VLDL
Cholesterol & Triglycerides
|
minimal
to none |
minimal
to none |
NC |
NC |
*See
Note 1 |
44% increased
total death rate; 36% increase in Gallbladder Cancer; Gallstones;
arrythmias, blood clots, muscle pain |
| Note1:
Atromid Significantly lowers Triglycerides in pts w/Trig in
1000-2000 mg/dl range |
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Zocor®
is a registered trademark of Merck & Co., Inc.
Baycol® is a registered trademark of Bayer. This product has
been removed from the market.
Lipitor®
is a registered trademark of Pfizer
Inc
Mevacor®
is a registered trademark of Merck & Co., Inc.
Pravachol®
is a registered trademark of Bristol-Myers Squibb Company
Colestid® is a registered
trademark of Pharmacia & Upjohn Company
|
