In a new study published in January 2003, Belgian researchers found that glucosamine sulfate reduced cartilge destruction by 60% in patients with mild wear-and-tear type of arthritis of the knee, known as OsteoArthritis (OA). Patients with the most severe OA had a 42% chance of developing a 0.5mm joint space narrowing every 3 years. (Osteoarthritis Cartilage 2003 Jan;11(1):1-5)

Glucosamine sulfate is a natural substance that is found in the joints and plays an important role in the maintenance of optimal cartilage health. In this three-year randomized, placebo-controlled, prospective study, of 212 patients with Osteoarthritis of the knee, half received 1500mg of oral glucosamine sulfate or a placebo. X-Ray analysis of these patients had revealed that there was no significant joint-space loss in the 106 patients on glucosamine sulphate (-0.06 mm) loss over 3 years, while the 106 patients on the placebo had a progressive joint-space narrowing (-0.31 mm) over the 3 years of the study. (Lancet 2001 Jan 27;357(9252):251-6)

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